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The Sustainable Development Goals (SDGs) recognize the importance of the inextricable link between social and ecological systems and human quality of life (QoL) and biodiversity. Therefore, understanding the feedback and interactions between biodiversity, nature’s contributions to people (NCP), and QoL plays a central role in advancing toward sustainability. In this context, the social-ecological systems (SES) approach has advanced on the subject, particularly in recent decades; however, much remains to be done to comprehensively understand these relationships and interactions, especially at local decision-making scales. In this thesis, through the lenses of the SES approach, the researcher investigates connections between biodiversity, NCP, and QoL in a tropical dry forest (TDF) on the Western coast of Mexico. This place is one of the best-known Neotropical TDF and has been the focus of SES research in the past 20 years, making it an excellent case study for exploring these connections. First, to approach the need for dialogue among different global and local scales and between global and local frameworks, the thesis identifies five key components of the SES dynamics-(1) ecological supply, (2) co-production of NCP, (3) management, (4) demand, and (5) benefits - and three local decision-making scales of analysis: individual plot, smallholder, and land tenure or governance units. A literature review was performed on the social-ecological indicators for the last 11 years in the Chamela-Cuixmala region to operationalize this framework. Second, this thesis uses social-ecological information to identify social-ecological systems units (SESU) spatially explicitly. A methodology was provided to spatially identify the components of social-ecological systems that environmental conditions and management practices have shaped at three previously stated relevant decision-making scales: plots owned by individuals, plot owners, and governance units. To do so, the research group identified and characterized: (1) ecological clusters (EC), (2) social-management clusters (SC), and (3) SESU in a TDF in western Mexico. The findings suggested that decision-makers (ejidatarios, i.e., type of ownership (related to agrarian reform), that in most cases the land allocated is small-smallholders) are bounded by the topographical characteristics and the public policies that determine communal (or private) governance and the number of resources available to them. Finally, the thesis examines the self-perceived QoL across the different SESU, finding 48 QoL items, which were grouped into six categories: 1) social capital, 2) economic capital, 3) agency, 4) nature, 5) peasant non-work activities, and 6) government and services; and two additional dimensions referred to obstacles and enablers of QoL. The researchers found that the more land cover transformation, the more enablers, and obstacles of QoL are identified; emphasis was put on economic capital to achieve QoL. As management is intensified and governance fosters individualism across SES, the higher the Current Welfare Index, and the lower the self-perceived material and non-material satisfaction.