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This thesis aims to provide a quantitative, cross-nationally comparative, longitudinal and multilevel study of the drivers and hindrances of national governments' anti-trafficking measures. In this research, both macro-level determinants of anti-trafficking enforcement and micro-level foundations of human trafficking are explored. In the manuscript, large-N comparative research examines how characteristics of countries interact with people's attitudes towards violence to better understand what creates environments that are more or less supportive of governments' anti-trafficking efforts. The results presented in the thesis speak not only in favor of studying this topic systematically and cross-nationally, addressing existing gaps in the literature but also in favor of combining macro- and micro-level evidence for developing more effective policy responses against human trafficking.