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Corporate irresponsibility is often the result of intentionally irresponsible strategies, decisions, or actions, which negatively affect an identifiable stakeholder or environment. For instance, these range from the violation of the human rights and labor standards to environmental damages. Organizations enacting irresponsible practices rely on different factors upon multiple levels (field, organizational, individual) and its interrelations as well as processes evolving within the organization leading to such behavior. However, reasons for the occurrence of and explanations for corporate irresponsibility so far have been limited, leaving a fragmented understanding of this phenomenon. This dissertation helps to improve the understanding and explanation of corporate irresponsibility by identifying driving patterns of corporate irresponsibility and showing how the interactions across multiple levels add to this phenomenon. Chapter 1 provides an overview of the topic of corporate irresponsibility, the theoretical approaches of this dissertation and an introduction to the chapters. The second chapter offers a review and analysis of the corporate irresponsibility literature. The chapter presents a variance model outlining the concept, antecedents, moderators and outcomes of recent corporate irresponsibility literature as well as the different factors across levels (field, organizational, individual). Chapter 2 offers a critical analysis of what we know by referring to current literature and offers insights on what we don't know by deriving main implications for future research on corporate irresponsibility. Chapter 3 enlarges the understanding of corporate irresponsibility introducing a process approach to explain how corporate irresponsibility evolves over time and under which conditions. Based on a qualitative meta-analysis findings converge around two distinct process paths of corporate irresponsibility, the opportunistic-proactive, and, the emerging-reactive, subdivided into three phases. Chapter 3 sheds different lights upon the phases of corporate irresponsibility and its underlying mechanisms. The final chapter 4 focuses on different underlying mechanisms driving the final downfall or demise of organizations, organizational failure. Chapter 4 offers an alternative explanation to the competing extremism and inertia mechanisms driving organizational failure in recent studies by suggesting that these explanations are rather complementary. In addition, chapter 4 enlarges the explanation of organizational failure identifying the role of conflict mechanisms and its interplay with rigidity mechanisms. In sum, this dissertation contributes to a better understanding of what causes and increases corporate irresponsibility, and a better explanation of how and why corporate irresponsibility and organizational failure emerges, develops, grows or terminates over time.